Breast Cancer: New protein linked to the spread discovered
Health Hunt Please change Orientation

Want to unlock the secrets of holistic health?

Yes, tell me more No, I like living in oblivion
Have you registered for India's most premier Health & Wellness event? Register your Brand today! Click Here
3
Notifications Mark all as read
Loader Image
No notifications found !
  • English
  • हिन्दी
3
Notifications Mark all as read
Loader Image
No notifications found !
Partner with Us
  • English
  • हिन्दी
Default Profile Pic

0 New Card

New Protein Linked To The Spread Of Breast Cancer Identified

Fitness
Vallari Sharma
3 min read

New Protein Linked To The Spread Of Breast Cancer Identified

  • 14 Likes
  • 0 Comment

According to the researchers, a certain protein that once deactivated could prevent the development of metastases for HER2-positive breast cancer, an aggressive kind of cancer.

Scientists at the University of Montreal have found a strong link between a certain protein and breast cancer.

A cancerous tumour develops when cells proliferate at an abnormally high rate and agglomerate in healthy tissues. Some of these cells are even more cunning. “Sometimes, cancer cells manage to leave the tumour to spread in the body, which complicates the evolution of the disease,” said researcher Cote.

Metastatic cells move more easily than most of their peers. They detach from a tumour, enter the bloodstream, and reach other organs such as the lungs, bones, or the brain. These cells are more difficult to destroy as they spread to other parts of the body and are more resistant to existing treatments. It has been observed that 90 per cent of breast-cancer deaths are caused by metastases.

The Canadian researchers have taken a step towards actually blocking metastases. In their study, the Institut de recherches cliniques de Montréal (IRCM) team demonstrated that a protein—AXL—influences the occurrence of metastasis in HER2-positive cancer, an aggressive type that accounts for 20 per cent of breast cancers.

In women with HER2-positive cancer, it was found that the less the AXL is present, the better the survival rate is.

“We determined that AXL is required for intravasation, extravasation, and growth at the metastatic site. We found that AXL is expressed in HER2+ cancers displaying epithelial-to-mesenchymal transition (EMT) signatures where it contributes to sustaining EMT. Interfering with AXL in a patient-derived xenograft (PDX) impaired transforming growth factor β (TGF-β)-induced cell invasion,” the authors wrote.

image1

“Based on this discovery, a treatment targeting AXL could reduce the risk of metastasis,” stated Cote.

According to the American Cancer Society, 1 in 8 women is likely to be diagnosed with breast cancer.

Here are some signs that can alert you to the fact that something may be wrong:

1. A lump that doesn’t disappear within a few days after your period


2. Breast pain


3. Swelling of the breast and around it


4. Dimpling of nipples that hurt


5. Leaky liquid from the nipples


6. Redness or thickening of the skin around the breast


If you observe any of these symptoms, you should definitely schedule a visit to the doctor.

Comment (0)

Submit Loader Image


    healthhunt

    We value your privacy

    We and our partners use technology such as cookies on our site to personalise content and ads, provide social media features, and analyse our traffic. Click below to consent to the use of this technology across the web. You can change your mind and change your consent choices at any time by returning to this site.

    Built byEngineer.ai

    Ask the Experts

    Some things to keep in mind

    Have a question related to the following? We’d love to help. Please submit your query, and feel free to leave your name or choose the option of staying anonymous. If our team of experts are able to respond, you will be notified via email, and an article might be published with the response.



    • Nutrition
    • Fitness
    • Organic Beauty
    • Mental Wellbeing
    • Love
    Cancel

    Keep me anonymous. Cancel

    Thank you! We look forward to answering your question.

    All responses can be seen in the ‘My Hunts’ section.